Sinclair Method Studies
Published on: 11/06/2025
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
What is the History of The Sinclair Method?
Bruce Rose Published on: 09/09/2025
The Sinclair Method, often referred to as TSM, has quietly revolutionised how we understand and treat Alcohol Use Disorder (AUD). Unlike traditional abstinence-only approaches, it offers a scientifically grounded, compassion-driven alternative. But where did it all begin?
The Sinclair Method (TSM)
The Sinclair Method: A Revolutionary Approach to Alcohol Harm Reduction
Published on: 03/04/2025
The Sinclair Method (TSM) is an evidence-based treatment for Alcohol Use Disorder (AUD) that diverges from traditional abstinence-focused approaches. Developed by Dr. John David Sinclair, TSM employs the opioid antagonist naltrexone to disrupt the brain's association between alcohol consumption and pleasurable sensations. This process, known as pharmacological extinction, gradually diminishes the desire to drink.
The Sinclair Method (TSM)
Why Support Is Essential for Success on The Sinclair Method: It's Not Just a Pill
Published on: 26/03/2025
When many people first hear about The Sinclair Method (TSM), they assume it's just about taking a pill. Simple, right? Pop naltrexone before drinking, and eventually lose the urge. But here's the truth: success on TSM isn't just about the medication — it's about the method, the mindset, and most importantly, the support.
The Sinclair Method (TSM)
The History of the Sinclair Method
Published on: 04/12/2024
This blog post will explore the history of the Sinclair Method, the clinical trials that followed, and its significance in the ongoing battle against alcoholism.
The Sinclair Method (TSM)
